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Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
Biomarkers in pulmonary hypertension
G Warwick1, P S Thomas, D H Yates
1Dept of Thoracic Medicine, St Vincent's Hospital, 390 Victoria Street, Darlinghurst, NSW 2010, Australia.
The European Respiratory Journal
|August 2, 2008
Summary
Recent advances in understanding pulmonary hypertension pathophysiology have led to new treatments. This review details important biomarkers for diagnosing and monitoring the condition, aiding clinical decisions.
Area of Science:
- Cardiology
- Pulmonology
- Biomarker Research
Background:
- Pulmonary hypertension (PH) pathophysiology understanding has advanced significantly.
- New therapeutic agents for PH are increasingly available.
- Traditional diagnostic and monitoring methods include echocardiography, right heart catheterization, functional class, and 6-minute walk test.
Purpose of the Study:
- To detail important biomarkers for pulmonary hypertension.
- To discuss the potential applications of these biomarkers in clinical practice.
- To review the evidence supporting the use of these biomarkers.
Main Methods:
- Literature review of recent advances in pulmonary hypertension.
- Identification and analysis of key biomarkers associated with PH.
- Evaluation of evidence for biomarker utility in diagnosis, severity assessment, and treatment response.
Main Results:
- Numerous biomarkers are elevated in pulmonary hypertension.
- These biomarkers show potential for aiding diagnosis and monitoring disease progression.
- Evidence supports the use of specific biomarkers in assessing treatment response.
Conclusions:
- Biomarkers offer a valuable addition to traditional methods for managing pulmonary hypertension.
- Further research into biomarker applications can refine diagnostic and therapeutic strategies.
- The integration of biomarkers can personalize patient care in pulmonary hypertension.
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