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Updated: Jul 3, 2026
07:48
An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Can we still afford bladder cancer?
Arnulf Stenzl1, Joerg Hennenlotter, David Schilling
1Department of Urology, Eberhard-Karls-University Tuebingen, Tuebingen, Germany. Urologie@med.uni-tuebingen.de
Current Opinion in Urology
|August 2, 2008
Summary
Bladder cancer treatment is costly, especially for nonmuscle invasive tumors. Strategies like photodynamic diagnosis, adjuvant therapies, and centralizing cystectomies can significantly reduce healthcare expenses and improve patient outcomes.
Area of Science:
- Oncology
- Health Economics
Background:
- Bladder cancer incurs substantial healthcare costs, with nonmuscle invasive tumors representing the largest financial burden.
- Follow-up care costs are lower than those associated with transurethral resection and cystectomy.
Purpose of the Study:
- To identify economic saving potentials in bladder cancer management.
- To review current strategies for cost reduction in treating nonmuscle invasive and advanced bladder cancer.
Main Methods:
- Review of cost-effectiveness in bladder cancer treatment.
- Analysis of strategies for reducing costs associated with nonmuscle invasive bladder cancer (NMIBC).
- Evaluation of centralization and predictive markers for cost savings in advanced bladder cancer.
Main Results:
- The greatest potential for cost reduction lies in the treatment and re-treatment of nonmuscle invasive bladder tumors.
- Cost savings are achievable through reduced hospital admissions, photodynamic diagnosis-assisted transurethral resection, and adjuvant chemo/immunoinstillation to prevent recurrence.
- Centralizing cystectomy to high-volume centers reduces complications and hospital stays, leading to cost savings.
Conclusions:
- Optimizing treatment for nonmuscle invasive bladder cancer offers significant cost-saving opportunities.
- Centralizing complex procedures like cystectomy improves outcomes and reduces expenses.
- Predictive markers can guide molecular therapies in advanced stages, avoiding ineffective treatment costs.
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