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Updated: Jul 3, 2026

Phenotypic Characterization of Macrophages from Rat Kidney by Flow Cytometry
Published on: October 18, 2016
Macrophages and hypoxia in human chronic kidney disease
1Department of Medicine and Therapeutics, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom. L.P.Erwig@abdn.ac.uk
Abstract:
Chronic kidney disease is characterized by progressive interstitial fibrosis, reduced blood flow, and tubular atrophy, which present a common pathway of destruction irrespective of the initial underlying pathology. There is comprehensive evidence that the interactions of infiltrating macrophages with resident tissue cells play a critical role in this process. A new study now describes the correlation between macrophages, capillary density, and interstitial scarring and suggests distinct differences in early and advanced renal disease.
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