Respiratory tract infections in children with recurrent episodes as preschoolers

M Söderström1, B Hovelius, K Prellner

  • 1Department of Community Health Sciences, Dalby, Sweden.

Insights

Children with recurrent respiratory tract infections (RTIs) as preschoolers experienced more frequent and longer RTIs in school. This suggests a long-term susceptibility to illness in these children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Recurrent respiratory tract infections (RTIs) in early childhood can indicate long-term health issues.
  • Understanding the trajectory of RTIs from preschool to school age is crucial for identifying at-risk children.

Purpose of the Study:

  • To prospectively investigate the occurrence and duration of RTIs in school-age children with a history of recurrent RTIs as preschoolers.
  • To compare the RTI incidence and patterns between children with and without a history of recurrent preschool RTIs.

Main Methods:

  • Prospective two-year follow-up of 41 school-age children with recurrent preschool RTIs.
  • Comparison group of 29 children with few or no preschool RTIs.
  • Data collection via parental diaries and medical consultations.

Main Results:

  • Children with recurrent preschool RTIs had significantly more frequent and longer episodes of RTIs during the follow-up period (p < 0.01).
  • The annual incidence of bacterial RTI decreased with age in the recurrent group, unlike the consistently low incidence in controls, with significant differences up to age eight (p < 0.01).
  • Acute otitis media predominated in preschoolers, and acute tonsillitis in school-age children; increased incidence of other diseases and complications was noted in the high-morbidity group.

Conclusions:

  • Certain children exhibit a high morbidity pattern, remaining susceptible to RTIs and other illnesses for extended periods.
  • Early recurrent RTIs may identify a subgroup of children with a prolonged susceptibility to infections.
  • This highlights the need for long-term monitoring and potential interventions for children with a history of recurrent RTIs.

Related Concept Videos

Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...