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Published on: February 23, 2014
Respiratory tract infections in children with recurrent episodes as preschoolers
M Söderström1, B Hovelius, K Prellner
1Department of Community Health Sciences, Dalby, Sweden.
Insights
Children with recurrent respiratory tract infections (RTIs) as preschoolers experienced more frequent and longer RTIs in school. This suggests a long-term susceptibility to illness in these children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Recurrent respiratory tract infections (RTIs) in early childhood can indicate long-term health issues.
- Understanding the trajectory of RTIs from preschool to school age is crucial for identifying at-risk children.
Purpose of the Study:
- To prospectively investigate the occurrence and duration of RTIs in school-age children with a history of recurrent RTIs as preschoolers.
- To compare the RTI incidence and patterns between children with and without a history of recurrent preschool RTIs.
Main Methods:
- Prospective two-year follow-up of 41 school-age children with recurrent preschool RTIs.
- Comparison group of 29 children with few or no preschool RTIs.
- Data collection via parental diaries and medical consultations.
Main Results:
- Children with recurrent preschool RTIs had significantly more frequent and longer episodes of RTIs during the follow-up period (p < 0.01).
- The annual incidence of bacterial RTI decreased with age in the recurrent group, unlike the consistently low incidence in controls, with significant differences up to age eight (p < 0.01).
- Acute otitis media predominated in preschoolers, and acute tonsillitis in school-age children; increased incidence of other diseases and complications was noted in the high-morbidity group.
Conclusions:
- Certain children exhibit a high morbidity pattern, remaining susceptible to RTIs and other illnesses for extended periods.
- Early recurrent RTIs may identify a subgroup of children with a prolonged susceptibility to infections.
- This highlights the need for long-term monitoring and potential interventions for children with a history of recurrent RTIs.
Abstract:
The occurrence of respiratory tract infections (RTI) in 41 school-age children, who had recurrent RTIs treated with antibiotics as preschoolers, was followed prospectively for two years through diary reports by parents and medical consultations, and compared with that in 29 children of the same age and socio-economic background, who had few or no such infections as preschoolers. During the two-year follow-up, a greater number of episodes of RTI and a longer mean duration of such episodes were reported in the diaries concerning the children with recurrent bacterial RTIs as preschoolers compared with the controls (p less than 0.01). The annual incidence of bacterial RTI from birth onwards decreased with age among the children with recurrent episodes as preschoolers, unlike in the control group, where the incidence remained consistently low, the difference in incidence being significant up to the age of eight years (p less than 0.01). Acute otitis media was the predominant bacterial RTI in preschoolers, and acute tonsillitis in school-age children. There was a tendency toward a greater incidence of other types of disease and complications/sequelae of infections among the RTI-afflicted group than among the controls, both as preschoolers and as school children. Our findings suggest that certain children constitute a group with high morbidity, susceptible to RTIs and other illnesses over a rather long period of years.
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