Effect of chemicals on the infectivity of chicken anaemia virus

None of five commercial disinfectants, invert soap, amphoteric soap, orthodichlorobenzene, iodine disinfectant and sodium hypochlorite, was completely effective in destroying the infectivity of chicken anaemia virus (CAV) in liver material at 5% concentration. However, the iodine disinfectant and sodium hypochlorite completely inactivated the virus in tissue culture (TC) material when used at 1% concentration. CAV was resistant to organic solvents such as methyl alcohol, ethyl alcohol, acetone and chloroform. Beta-propiolactone and glutaraldehyde inactivated CAV. Fumigation with formaldehyde for 24 h only partly inactivated both liver and TC materials. It is presumed very hard to disinfect CAV in poultry facilities.