Related Experiment Video
Updated: Aug 1, 2026

09:24
In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration
Published on: February 23, 2019
[Arsenical necrosis still exists... I have seen it]
1Groupe Hospitalier Cochin, Paris.
Actualites Odonto-Stomatologiques
|June 1, 1991
Summary
Arsenic necroses, a condition caused by arsenic anhydride for pulp removal, were common until recently. This review examines the historical evolution of understanding and managing this dental complication.
Area of Science:
- Dentistry
- Toxicology
- Medical History
Background:
- Arsenic anhydride was historically employed for dental pulp devitalization.
- This method aimed to facilitate pulp removal in endodontic procedures.
Observation:
- The use of arsenic anhydride led to significant tissue necrosis.
- Arsenic necroses represent a notable complication of this past dental practice.
Findings:
- The historical application of arsenic anhydride for pulp removal is linked to arsenic necroses.
- Understanding the evolution of concepts surrounding this technique is crucial.
Implications:
- Historical dental practices inform current safety standards.
- Reviewing past complications aids in preventing future iatrogenic injuries.
- The decline of arsenic anhydride highlights advancements in safer endodontic materials.
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