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Dialysis disequilibrium syndrome: a consideration in patients with hydrocephalus
Thomas Flannery1, Alireza Shoakazemi, Brian McLaughlin
1Department of Neurosurgery, Royal Hospitals Belfast Trust, Belfast, Ireland. tomflannery@fsmail.net
Abstract:
Dialysis disequilibrium syndrome is a rare neurological manifestation of intermittent hemodialysis. Urea removal occurs more slowly across the blood-brain barrier than from the plasma, generating an osmotic gradient that promotes water movement into the brain and cerebral edema. The authors report the development of dialysis disequilibrium syndrome in a patient with spina bifida and an adequately functioning shunt.
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