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Related Concept Videos

Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
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Transthoracic Echocardiography (TTE)
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Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
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Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

Review Showed That Better Screening Is Still Needed for a Minority of Severe and Critical Congenital Heart Defects.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

We still have a way to go when it comes to detecting critical heart defects.

Acta paediatrica (Oslo, Norway : 1992)·2023
Same author

When false positive tests have a positive aspect.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2021
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Newborn pulse oximetry screening is not just for heart defects.

Acta paediatrica (Oslo, Norway : 1992)·2015
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Nordic pulse oximetry screening--implementation status and proposal for uniform guidelines.

Acta paediatrica (Oslo, Norway : 1992)·2014
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[Critical heart defects in newborns overlooked].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2014

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A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
08:19

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

Published on: December 16, 2022

Critical heart defects--the diagnostic challenge.

Alf Meberg1

  • 1Department of Paediatrics, Vestfold Hospital, Tønsberg, Norway. alfmeb@start.no

Acta Paediatrica (Oslo, Norway : 1992)
|August 2, 2008
PubMed
Summary

Early detection of congenital heart defects (CHDs) is crucial. Combining pulse oximetry, clinical exams, and echocardiography before hospital discharge can identify CHDs in newborns, preventing missed diagnoses.

Area of Science:

  • Neonatal Medicine
  • Pediatric Cardiology
  • Medical Diagnostics

Background:

  • Congenital heart defects (CHDs) are often undetected in newborns before hospital discharge.
  • Undiagnosed CHDs pose significant risks to infant health.
  • Current screening methods may not be universally effective.

Purpose of the Study:

  • To evaluate strategies for improving the early detection of congenital heart defects in newborns.
  • To assess the effectiveness of combining pulse oximetry, clinical examination, and echocardiography for postnatal screening.

Main Methods:

  • Review of strategies including prenatal ultrasound and universal pulse oximetry screening.
  • Analysis of combining first-day-of-life pulse oximetry, clinical examination, and echocardiography for suspect cases.

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Last Updated: Jul 3, 2026

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  • Consideration of universal echocardiography screening for cost-effectiveness.

    • Main Results:

    • Improved prenatal ultrasound and universal pulse oximetry screening are likely to reduce missed CHD diagnoses.
    • A combined approach of pulse oximetry, clinical examination, and echocardiography on the first day of life is a rational strategy for detecting heart defects.
    • Universal echocardiography screening may not be cost-effective due to resource demands.

    Conclusions:

    • Early postnatal detection of CHDs can be achieved through a multi-faceted screening approach before hospital discharge.
    • While universal screening has benefits, a targeted approach for suspect cases is more practical and cost-effective.
    • Integrating diagnostic tools like pulse oximetry and echocardiography is key for timely intervention in congenital heart disease.