Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Noonan-CFC controversy.

G Neri, M Zollino, J F Reynolds

    American Journal of Medical Genetics
    |June 1, 1991
    PubMed
    Summary
    This summary is machine-generated.

    Noonan syndrome and cardio-faciocutaneous (CFC) syndrome are distinct conditions. Clinical evidence supports their separation within the Noonan/congenital lymphedema spectrum, despite phenotypic similarities.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Development of magnesium-doped zinc oxide nanopowders for conductometric acetone gas sensors.

    RSC advances·2025
    Same author

    Resistive nanostructured W<sub>18</sub>O<sub>49</sub> gas sensors: an overview.

    RSC advances·2025
    Same author

    Neuroprotection beyond intraocular pressure: game changer or quiet addiction.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2025
    Same author

    Effect of the <i>in situ</i> synthesis of vanadium oxide nanowires on the electrical properties of hybrid nanocomposites based on synthetic carbon matrices.

    RSC advances·2025
    Same author

    Ammonia gas sensors based on undoped and Ca-doped ZnO nanoparticles.

    RSC advances·2024
    Same author

    Novel nanosynthesis of In<sub>2</sub>O<sub>3</sub> and its application as a resistive gas sensor for sevoflurane anesthetic.

    Journal of materials chemistry. B·2020

    Area of Science:

    • Medical Genetics
    • Clinical Medicine
    • Dermatology

    Background:

    • Noonan syndrome and cardio-faciocutaneous (CFC) syndrome are often considered distinct.
    • Phenotypic and genetic similarities have led to debate regarding their separation.

    Purpose of the Study:

    • To review clinical evidence supporting the distinction between Noonan syndrome and CFC syndrome.
    • To clarify the nosological classification of these related developmental disorders.

    Main Methods:

    • Review of existing clinical data and literature.
    • Comparative analysis of phenotypic features.

    Main Results:

    • Clinical evidence supports Noonan syndrome and CFC syndrome as separate entities.

    Related Experiment Videos

  • Both conditions are part of a broader spectrum of Noonan/congenital lymphedema phenotype.

    • Conclusions:

    • Noonan syndrome and CFC syndrome represent distinct diagnoses.
    • Understanding their separation is crucial for accurate diagnosis and management within the Noonan/congenital lymphedema spectrum.