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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Molecular epidemiology of dengue virus type 3 in Northern South America: 2000--2005
Tadeusz Kochel1, Patricia Aguilar, Vidal Felices
1United States Naval Medical Research Center Detachment, Unit 3800, APO AA 34031, American Embassy, Lima, Peru. tad.kochel@med.navy.mil
Abstract:
A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.
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