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Repeatability of health economic data in COPD
Rune Nielsen1, Ane Johannessen, Hege Marie Schnelle
1Institute of Medicine, University of Bergen, Haukeland University Hospital, N-5021 Bergen, Norway. rune.nielsen@med.uib.no
Self-reported health economic data from chronic obstructive pulmonary disease (COPD) patients shows significant variability. This impacts the reliability of cost and utilization data in research and clinical settings.
Area of Science:
- Health Economics
- Pulmonology
- Patient-Reported Outcomes
Background:
- The precision of self-reported health economic data is not well understood.
- Accurate economic data is crucial for healthcare research and policy.
Purpose of the Study:
- To assess the repeatability of self-reported health economic cost and utilization data in individuals with chronic obstructive pulmonary disease (COPD).
Main Methods:
- 29 patients with COPD were interviewed twice, 12 weeks apart, by a physician and nurse in random order.
- Interviews captured healthcare utilization, costs, sick leave, exacerbations, and quality of life (QoL).
- Kappa statistics and 95% limits of agreement were used to evaluate data consistency.
Main Results:
- Repeatability varied across different data points, with sick leave showing perfect agreement (kappa=1.00) and leisure time showing lower agreement (kappa=0.54).
- Physicians reported fewer exacerbations and healthcare contacts than nurses (p=0.01 and p=0.05).
- Wide 95% limits of agreement were observed for drug costs (-690 to +710 NOK) and healthcare provider costs (-1200 to +899 NOK).
Conclusions:
- Self-reported economic data in COPD patients exhibits substantial variability.
- This variability necessitates careful consideration during the analysis of interview-based cost data and in the design of health economic studies.
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