[Morphometric study of transitional carcinoma of the bladder (II): analysis of 95 infiltrating tumors]

The nuclear size of 95 infiltrating carcinomas of the bladder were studied morphometrically. There were 34 of the infiltrating papillary type and 61 pure infiltrating tumors. The nuclear size was found to be greater deeper into the tumor. Similarly, the higher the histologic grade, the larger the nuclear size. Grade IV tumors, however, were not greater than grade III. The foregoing finding prompted us to classify grade IV tumors as undifferentiated rather than as transitional cell tumors. A better prognosis was observed for stage T2 and T3A tumors with a nuclear size less than or equal to 30 microns 2.