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Immunocytochemistry and Immunohistochemistry

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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Updated: Jul 3, 2026

Optimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry

Optimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry

Published on: July 26, 2019

[Morphological and immunohistochemical pitfalls in pathology. Introduction]

Pierre Brousset¹, Camille Laurent, Paul Caverivière

¹Service d'anatomie et cytologie pathologiques, CHU Purpan, 31059 Toulouse cedex, France. brousset.p@chu-toulouse.fr

Annales De Pathologie

|August 5, 2008

Summary

No abstract available in PubMed .

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