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Corneal choristoma with microphthalmos.

T Murata1, T Ishibashi, Y Ohnishi

  • 1Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|August 1, 1991
PubMed
Summary

Two rare cases of corneal choristoma, a condition where ocular structures are replaced by skin tissue, led to microphthalmos. Computed tomography aided in assessing the extent of ocular involvement.

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Area of Science:

  • Ophthalmology
  • Pathology
  • Developmental Biology

Background:

  • Corneal choristoma is a rare congenital anomaly.
  • Microphthalmos is a condition of incomplete ocular development.

Observation:

  • Two cases of corneal choristoma replacing the cornea, anterior chamber, and iris with cutaneous and subcutaneous tissue are presented.
  • Case 1 involved a dermoid choristoma with skin appendages and fibrofatty tissue extending into the vitreous, containing retinal fragments.
  • Case 2 presented a dermislike choristoma lacking skin appendages.

Findings:

  • The abnormal cutaneous tissues impeded normal ocular growth, resulting in microphthalmos.
  • Computed tomography proved valuable in evaluating the extent of ocular and intraocular malformations.

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Implications:

  • Understanding the pathogenesis of corneal choristoma is crucial for diagnosis and management.
  • This highlights the importance of advanced imaging in complex congenital eye malformations.