Living donor liver transplantation with hyperreduced left lateral segments

Area of Science:

• Pediatric Surgery
• Hepatology
• Organ Transplantation

Background:

• Pediatric liver transplantation utilizes left lateral segment grafts (segments II and III).
• Large-for-size grafts pose challenges in small infants undergoing liver transplantation.
• Reduced left lateral segmental liver transplantation was developed to address this issue.

Purpose of the Study:

• To evaluate the feasibility and application of hyperreduced left lateral segment grafts in pediatric living donor liver transplantation.
• To present surgical experiences with hyperreduced grafts as an alternative technique for infants with end-stage liver disease.

Main Methods:

• Surgical technique involving further reduction of left lateral segment liver grafts.
• Living donor liver transplantation performed in three pediatric cases using hyperreduced grafts.

Main Results:

• Successful transplantation in three infants using hyperreduced left lateral segment grafts.
• Demonstrated the possibility of supplying adequate hyperreduced grafts for small infants.

Conclusions:

• Hyperreduced left lateral segment grafts are a viable alternative surgical technique for pediatric liver transplantation.
• This approach effectively mitigates the problem of large-for-size grafts in infants requiring liver transplants.