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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Related Experiment Video

Updated: Jul 3, 2026

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

Updates in non-small cell lung cancer.

Suzanne Walker1

  • 1School of Nursing, University of Pennsylvania, Philadelphia, PA, USA. suzanne.walker@uphs.upenn.edu

Clinical Journal of Oncology Nursing
|August 5, 2008
PubMed
Summary

Lung cancer remains a leading cause of cancer death. Advances in targeted therapies and genetic blueprinting offer new hope for improving survival rates in non-small cell lung cancer (NSCLC) patients.

Area of Science:

  • Oncology
  • Pulmonology
  • Cancer Research

Background:

  • Lung cancer is the leading cause of cancer-related mortality globally.
  • Non-small cell lung cancer (NSCLC) accounts for over 80% of lung cancer diagnoses.
  • Current five-year survival rates for lung cancer remain low at 15%.

Purpose of the Study:

  • To provide an overview of recent advancements in non-small cell lung cancer (NSCLC).
  • To highlight emerging treatment strategies, including targeted therapies and genetic profiling.
  • To emphasize the crucial role of nurses in managing NSCLC patients.

Main Methods:

  • Review of current literature on NSCLC prevention, detection, and treatment.
  • Focus on novel therapeutic approaches and diagnostic technologies.

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Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
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Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer

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Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
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Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
07:59

Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer

Published on: September 8, 2023

  • Discussion of nursing implications in patient care.

    • Main Results:

    • Significant progress in targeted therapy development for NSCLC.
    • Advancements in genetic blueprinting enabling personalized treatment strategies.
    • Identification of key areas for nursing intervention and education.

    Conclusions:

    • New treatment strategies, particularly targeted therapies and genetic profiling, show promise for improving NSCLC outcomes.
    • Continuous education for healthcare professionals, especially nurses, is vital for optimal patient management.
    • Further research and implementation of these advances are critical to enhance survival rates.