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Related Concept Videos

Signs of Puberty01:27

Signs of Puberty

Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
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Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Hormones and Bone Tissue01:17

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Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
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[Bone mass in puberty].

Masaru Kaga1, Hiroko Kamimura

  • 1Okayama University, Faculty of Education, Akasaka Junior High School.

Clinical Calcium
|August 5, 2008
PubMed
Summary

During puberty, bone mass increases with sex hormones, peaking in late teens. Ultrasonic tibia measurements reveal age-dependent bone speed of sound (SOS) increases, highlighting the importance of nutrition and activity for bone health.

Area of Science:

  • Pediatrics
  • Orthopedics
  • Bone Biology

Background:

  • Bone mass accrual is crucial during childhood and adolescence.
  • Pubertal hormonal surges significantly influence bone development and peak bone mass.
  • Cortical bone assessment is vital for understanding bone health trajectories.

Purpose of the Study:

  • To establish normative data for speed of sound (SOS) in the tibia using ultrasound in pediatric and adolescent populations.
  • To investigate the age-related changes in cortical bone properties during growth.
  • To identify potential periods of relative bone fragility during rapid growth phases.

Main Methods:

  • Utilized quantitative ultrasound (QUS) to measure the speed of sound (SOS) in the tibia.
  • Analyzed age- and sex-specific data from a cohort of children and adolescents.

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  • Correlated SOS changes with pubertal development and peak height velocity.
  • Main Results:

    • Speed of sound (SOS) in the tibia demonstrated a significant age-dependent increase in both males and females.
    • The most substantial increase in SOS occurred approximately one year post-peak height velocity.
    • A transient period of relative bone fragility was identified during rapid linear growth, preceding maximal bone strength gain.

    Conclusions:

    • Ultrasound-based tibial SOS provides a valuable, non-invasive method for assessing cortical bone development in youth.
    • Optimal physical activity and nutrition during puberty are critical for maximizing bone mass and strength.
    • Understanding growth dynamics is essential for preventing bone fragility in adolescents.