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Published on: November 10, 2017

Changes in lipid profile of patients referred to a cardiac rehabilitation program

Nizal Sarrafzadegan1, Katayoun Rabiei, Ali Kabir

  • 1Department of Medicine, WHO Collaborating Center.

European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology
|August 5, 2008
PubMed

Insights

Cardiac rehabilitation programs significantly improve lipid profiles in Iranian cardiovascular patients. These programs enhance total cholesterol, LDL, HDL, and triglycerides, with added benefits from antilipid medications.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Public Health

Background:

  • Cardiac rehabilitation programs (CRP) show benefits for cardiovascular disease (CVD) patients.
  • The impact of CRP on lipid profiles in CVD patients remains unclear.
  • This study focuses on the Iranian population.

Purpose of the Study:

  • To evaluate the effect of a comprehensive CRP on the lipid profile of Iranian patients with cardiovascular disease.
  • To assess improvements in biochemical, functional, and psychosocial parameters post-CRP.

Main Methods:

  • A self-controlled descriptive study design was employed.
  • 547 patients with documented coronary heart disease were evaluated before and after a 24-session CRP.
  • Data collected between 1998 and 2003, including patients on antilipid drugs.

Main Results:

  • CRP significantly improved total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglyceride (TG) levels.
  • CRP contributed to lipid normalization: 34.9% for TC, 17.7% for LDL, and 27.2% for TG (P<0.001).
  • Antilipid drugs provided additional normalization: 9.7% for TC, 1.8% for LDL, and 7.3% for TG.

Conclusions:

  • Comprehensive CRP effectively improves lipid profiles (TC, TG, LDL, HDL) in Iranian CVD patients.
  • CRP benefits lipid profiles even without antilipid drugs.
  • Antilipid therapy can further enhance the positive effects of CRP on lipid profiles.
Abstract

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