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Motion characterization of aortic wall and intimal flap by ECG-gated CT in patients with chronic B-dissection

Maria-Katharina Ganten1, Tim F Weber, Hendrik von Tengg-Kobligk

  • 1Department of Radiology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. m.ganten@dkfz-heidelberg.de

European Journal of Radiology
|August 6, 2008
PubMed

Insights

Dynamic computed tomography (CT) angiography reveals pulsatile aortic changes and intimal flap motion in patients with chronic aortic dissection type Stanford-B (ADB). Aortic distensibility was not significantly affected by diameter or flap presence.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Vascular Surgery

Background:

  • Chronic aortic dissection type Stanford-B (ADB) requires accurate assessment of aortic function.
  • Dynamic imaging may offer functional insights beyond static anatomical evaluation.

Purpose of the Study:

  • To assess the utility of dynamic computed tomography (CT) angiography in evaluating functional vessel information in patients with ADB.
  • To investigate aortic distensibility and intimal flap motion using ECG-gated CT-angiography.

Main Methods:

  • 32 patients with ADB underwent ECG-gated CT-angiography.
  • Semiautomatic segmentation was used to analyze cross-sectional area changes and wall distensibility.
  • Intimal flap oscillation was analyzed in relation to aortic diameter and distensibility.

Main Results:

  • Successful aortic segmentation was achieved in all patients.
  • Aortic distensibility was found to be independent of aortic diameter or the presence of an intimal flap.
  • Analysis revealed pulsatile motion of the intimal flap, with up to a 29% decrease in true lumen short axis diameter.

Conclusions:

  • Dynamic, ECG-gated CT-angiography effectively demonstrates pulsatile aortic changes and intimal flap motion in ADB.
  • Aortic distensibility in ADB appears to be independent of diameter or intimal flap presence.
  • Further follow-up studies are warranted to correlate these findings with potential complications.
Abstract

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