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Updated: Jul 3, 2026
Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
Published on: May 23, 2025
Expression, purification, crystallization and preliminary X-ray analysis of an NAD-dependent
Paul R Elliott1, Shabaz Mohammad, Helen J Melrose
1Henry Wellcome Laboratories for Structural Biology, University of Leicester, Leicester LE19HN, England.
Abstract:
Helicobacter pylori is a dangerous human pathogen that resides in the upper gastrointestinal tract. Little is known about its metabolism and with the onset of antibiotic resistance new treatments are required. In this study, the expression, purification, crystallization and preliminary X-ray diffraction of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from H. pylori are reported.
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