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Published on: August 21, 2021
Activated, type I collagen (CellerateRx) and its effectiveness in healing recalcitrant diabetic wounds: a case
Martin I Newman1, Larry G Baratta, Kimberly Swartz
1Department of Plastic and Reconstructive Surgery, Cleveland Clinic Florida, Weston, FL, USA.
Objective:
To review the authors' experience with activated type I collagen in the treatment of recalcitrant wounds in the diabetic population resulting from minor trauma and/or venous stasis disease. With regard to activated collagen, CellerateRx's patented activated collagen fragments are a fraction of the size of the native collagen molecules and particles found in other products, delivering the benefits of collagen to the body immediately.
Design:
A 2-case presentation wherein patients were treated with CellerateRx (activated, fragmented, and nonintact type I collagen) in a gel and powder form.
Subjects:
Two middle-aged diabetic male patients with lower extremity wounds refractory to conservative wound care.
Results:
Complete resolution of recalcitrant wounds in 6 to 7 weeks.
Conclusions:
Wound resolution was evident when using the authors' practice protocol, which includes the application of activated collagen. The inherent properties of type I collagen may contribute to a more rapid healing process.
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