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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Bronchoscopy is associated with decreased mesenteric arterial flow
Ali Nayci1, Sibel Atis, Meltem Nass Duce
1Department of Pediatric Surgery, Mersin University School of Medicine, Mersin Turkey. anayci@mersin.edu.tr
Critical Care Medicine
|August 6, 2008
Summary
Fiberoptic bronchoscopy may reduce mesenteric blood flow, increasing risks of ischemia and bacterial translocation. This study monitored blood flow and ischemia markers post-procedure in patients.
Area of Science:
- Gastroenterology
- Pulmonology
- Surgical Critical Care
Background:
- Fiberoptic bronchoscopy (FOB) is a common diagnostic procedure.
- A potential complication of FOB is mesenteric ischemia and bacterial translocation, though not well-established.
Purpose of the Study:
- To investigate the impact of FOB on mesenteric blood flow.
- To assess markers of ischemia-reperfusion injury and bacterial translocation post-FOB.
Main Methods:
- 47 patients undergoing FOB were studied.
- Mesenteric blood flow was assessed using Doppler sonography.
- Oxidative stress markers, blood gases, and blood cultures were analyzed pre- and post-procedure.
Main Results:
- FOB led to significant decreases in PaO2 and mesenteric blood flow volume.
- Increased markers of oxidative stress (myeloperoxidase, malondialdehyde) and indices of vascular resistance were observed.
- Bacteremia occurred in 6.4% of patients, with 19.1% developing fever.
Conclusions:
- Fiberoptic bronchoscopy is associated with reduced mesenteric blood flow.
- This reduction may elevate the risk of mesenteric ischemia and bacterial translocation in patients.
