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Related Concept Videos

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Cross-reactivity

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Viral Recombination

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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
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Related Experiment Video

Updated: Jul 3, 2026

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
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Published on: May 29, 2016

Antigenic relationships between fowl enteroviruses.

M Decaesstecker1, G Meulemans

  • 1National Institute for Veterinary Research, Brussels, Belgium.

Avian Pathology : Journal of the W.V.P.A
|October 1, 1989
PubMed
Summary
This summary is machine-generated.

Avian nephritis virus shares antigenicity with other entero-like viruses. However, it is distinct from avian encephalomyelitis virus, based on serological testing.

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Area of Science:

  • Veterinary Virology
  • Immunology
  • Pathogen Discovery

Background:

  • Avian nephritis virus (ANV) is an avian pathogen.
  • Entero-like viruses can cause significant disease in poultry.
  • Understanding antigenic relationships is crucial for disease control.

Purpose of the Study:

  • To investigate the antigenic relationship between the G-4260 strain of ANV and other entero-like viruses.
  • To differentiate ANV from avian encephalomyelitis virus (AEV) using serological methods.

Main Methods:

  • Immunofluorescence assays were employed to detect viral antigens.
  • Seroneutralisation tests were performed to assess virus-neutralizing antibody activity.
  • Comparative analysis of viral cross-reactivity was conducted.

Main Results:

  • A significant antigenic cross-relationship was identified between ANV (G-4260 strain) and three other entero-like particles.
  • These related viruses included one isolated by McNulty et al. and two laboratory isolates (entero PV2 and entero 3).
  • No antigenic cross-reactions were observed between ANV and avian encephalomyelitis virus.

Conclusions:

  • The G-4260 strain of ANV shares antigenic properties with certain entero-like viruses.
  • ANV is antigenically distinct from avian encephalomyelitis virus.
  • These findings aid in the classification and diagnosis of avian enteric viruses.