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Updated: Jul 3, 2026

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
07:05

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

Published on: August 23, 2024

Natural antioxidants

Diane S Berson1

  • 1Weill Medical College of Cornell University, Ithaca, NY, USA. dsb2001@med.cornell.edu

Journal of Drugs in Dermatology : JDD
|August 7, 2008
PubMed

Insights

Topical antioxidants can combat skin damage from oxidative stress. Natural ingredients like soy and green tea show promise in treating photoaging and other skin conditions.

Area of Science:

  • Dermatology
  • Biochemistry
  • Pharmacology

Background:

  • Skin is constantly exposed to oxidative stress, damaging DNA, lipids, and proteins.
  • Natural skin antioxidants can be depleted by environmental factors, leading to oxidative damage.
  • Topical antioxidants can replenish skin's antioxidant capacity and prevent damage.

Purpose of the Study:

  • To review natural antioxidant ingredients for topical use.
  • To summarize their active components, properties, and clinical effectiveness.
  • To assess their potential in treating oxidative stress-induced dermatoses.

Main Methods:

  • Literature review and summary of existing clinical trials.
  • Focus on natural ingredients: soy, feverfew, mushroom extracts, teas, CoffeeBerry, Pycnogenol, and Polypodium leucotomos.
  • Analysis of pharmacologic properties and clinical efficacy.

Main Results:

  • Several natural ingredients possess antioxidant and anti-inflammatory properties.
  • These compounds show potential in treating photoaging and other oxidative stress-related skin conditions.
  • Clinical trials indicate promising efficacy for topical application.

Conclusions:

  • Natural antioxidants are valuable for replenishing skin's defense against oxidative stress.
  • Topical application of these ingredients offers a promising therapeutic strategy.
  • Further research supports their use in managing dermatoses caused by oxidative damage.

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