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Reference materials--a main element in a coherent reference measurement system.

R Dybkaer1

  • 1Klinisk-Kemisk Afdeling, Frederiksberg Hospital, Denmark.

European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies
|April 1, 1991
PubMed
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Establishing reliable analytical measurements requires a robust reference measurement system and well-characterized reference materials. This study clarifies reference material characteristics and proposes standardized nomenclature to improve measurement accuracy and consistency.

Area of Science:

  • Analytical Chemistry
  • Metrology
  • Materials Science

Background:

  • Analytical reliability hinges on a coherent reference measurement system.
  • Reference materials are crucial measurement standards within this system.
  • Existing characterization and terminology for reference materials present challenges.

Purpose of the Study:

  • To define and categorize the characteristics of reference materials.
  • To identify and address problem areas in reference material characterization.
  • To propose a systematic nomenclature for reference materials.

Main Methods:

  • Detailed analysis of general, specific, and additional characteristics of reference materials.
  • Identification of key problem areas including analyte definition, purification, matrix, value assignment, and nomenclature.

Related Experiment Videos

  • Review and critique of current terminology.

    • Main Results:

    • Reference materials are characterized by general, specific, and additional properties.
    • Problem areas such as analyte definition, purification, matrix, value assignment, and nomenclature were identified.
    • Ambiguous terminology was presented and a systematic structure of descriptive names was proposed.

    Conclusions:

    • A clear understanding and consistent characterization of reference materials are essential for analytical reliability.
    • Standardized nomenclature will enhance clarity and reduce ambiguity in scientific communication.
    • The proposed systematic structure provides a framework for improved reference material description.