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Published on: March 21, 2013
[Ambulatory blood pressure monitoring in clinical practice]
Fabio Angeli1, Gianpaolo Reboldi, Salvatore Repaci
1Struttura Complessa di Cardiologia, Ospedale S. Maria della Misericordia, Università degli Studi, Perugia. fangeli@cardionet.it
Insights
Ambulatory blood pressure (BP) monitoring better predicts cardiovascular risk than traditional office BP measurements. This method offers superior insight into hypertension-related organ damage and patient outcomes.
Area of Science:
- Cardiology
- Hypertension Research
- Clinical Diagnostics
Context:
- Traditional arterial hypertension diagnosis relies on office blood pressure (BP) measurements.
- 24-hour noninvasive ambulatory BP monitoring is gaining prominence for essential hypertension management.
- Prospective studies highlight ambulatory BP's independent association with cardiovascular disease risk.
Purpose:
- To review the prognostic value of ambulatory BP monitoring compared to office BP.
- To discuss the interpretation of ambulatory BP monitoring results.
- To explore the link between ambulatory BP and hypertension-related organ damage.
Summary:
- Ambulatory BP monitoring is a superior predictor of cardiovascular morbidity and mortality versus office BP, even after adjusting for risk factors.
- Its enhanced prognostic value may stem from a stronger correlation with hypertension-induced organ damage (e.g., left ventricular mass, intima-media thickness, microalbuminuria).
- This review will cover the advantages of ambulatory over clinic BP in predicting outcomes and optimal interpretation strategies.
Impact:
- Highlights the clinical utility of ambulatory BP monitoring for improved cardiovascular risk assessment in hypertensive patients.
- Provides evidence for adopting ambulatory BP monitoring as a key diagnostic tool.
- Informs clinical practice regarding the interpretation of ambulatory BP data for better patient management and outcomes.
Abstract:
Traditionally, diagnosis and management of arterial hypertension are based on blood pressure (BP) measurements taken in the physician's office. However, 24-h noninvasive ambulatory BP monitoring is increasingly used in patients with essential hypertension. Several prospective studies provided unequivocal evidence of an independent association between ambulatory BP and risk of cardiovascular disease in the general population and hypertensive patients. Ambulatory BP is a better predictor of cardiovascular morbidity and mortality than office BP after adjustment for traditional cardiovascular risk factors such as age, sex, smoking status, baseline office BP, and use of antihypertensive drugs. The more accurate prognostic value of ambulatory BP may be related to the closer association with hypertension-related organ damage such as left ventricular mass, intima-media thickness, and microalbuminuria. The superiority of ambulatory over clinic BP in predicting clinical outcome and the most appropriate way of interpreting results of ambulatory BP monitoring will be discussed in this review.
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