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[Patellofemoral pain].

V Sanchis-Alfonso¹

¹Orthopaedic Surgeon, Department of Orthopaedics, Hospital Arnau de Vilanova, San Clemente 12, 46015 Valencia, Spain. sanchis_vicalf@cv.gvd.es

|August 7, 2008

Summary

Anterior knee pain in young patients may stem from brief ischemia in the lateral retinaculum, causing nerve growth. This aligns with the tissue homeostasis theory for pain development.

Area of Science:

Orthopedics
Pain Pathogenesis
Neuroscience

Background:

Anterior knee pain is common in young individuals.
Existing theories on its pathogenesis are being refined.

Purpose of the Study:

To review current knowledge on anterior knee pain pathogenesis in young patients.
To introduce and support a novel

Main Methods:

Review of existing literature on anterior knee pain.
Development of a "neural model" for pain genesis.
Analysis of findings related to neural proliferation and ischemia.

Main Results:

Periodic, short ischemia in the lateral retinaculum is hypothesized to cause anterior knee pain.

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This ischemia may trigger the proliferation of nociceptive axons (substance P-positive nerves).

Neural proliferation often occurs in a perivascular location.

Conclusions:

The proposed "neural model" offers a new explanation for anterior knee pain.
Findings support the tissue homeostasis theory in explaining pain genesis.
Further research into retinacular ischemia and neural changes is warranted.