Related Experiment Video

Updated: Jul 3, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method

Published on: September 16, 2017

Golimumab, a fully human monoclonal antibody against TNFalpha

Gabor Hutas1

  • 1Rush University Medical Center, Department of Orthopedic Surgery, MC102, Cohn Building, Room 712, 1735 W Harrison St, Chicago, IL 60612, USA. gaborhutas@gmail.com

Current Opinion in Molecular Therapeutics
|August 7, 2008
PubMed

Centocor Inc and licensees Schering-Plough Corp, Mitsubishi Tanabe Pharma Corp and Janssen Pharmaceutical KK are developing golimumab, a fully human mAb antibody against TNFalpha, for the potential treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and ulcerative colitis. Golimumab is currently in phase III clinical trials for RA, PsA and AS and preliminary data have shown an improvement in a number of physical functions, disease activity, productivity and quality-of-life measurements.

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