Related Experiment Video
Updated: Jul 3, 2026

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
Published on: March 22, 2016
Down syndrome and Alzheimer's disease: children grow older
H Barry Waldman1, Steven P Perlman, Robert E Roesch
1Department of General Dentistry, Stony Brook University, NY, USA.
Abstract:
The co-morbidity of Down syndrome and Alzheimer's disease is an increased reality due to an increased life expectancy among individuals with Down syndrome and the very early onset of Alzheimer's disease in this population. In addition, deinstitutionalization and mainstreaming these patients into the general community setting has meant that individuals with Down syndrome are dependent upon neighborhood practitioners for needed dental services. This article presents a review of the natural history of Down syndrome and Alzheimer's disease, along with the particular signs and symptoms of individuals with these co-morbidities and the implications for dental practice.
Related Concept Videos
Alzheimer Disease l: Introduction
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer Disease ll: Pathophysiology
Cognitive Development During Adulthood
Dementia l: Introduction
Huntington Disease l: Introduction
