Paediatric renal stone disease in Tunisia: a 12 years experience

Akram Alaya1, Abdellaatif Nouri, Mohamed Fadhel Najjar

  • 1Department of Biochemistry and Toxicology, University Hospital, Fattouma Bourguiba Hospital, Monastir, Tunisia. akram_alaya@yahoo.co.uk

Insights

Urinary tract infections are increasingly common in Tunisian children, leading to a rise in struvite and ammonium urate stones. This study tracked stone disease evolution in Tunisia over 12 years.

Area of Science:

  • Urology
  • Pediatric Nephrology
  • Epidemiology

Background:

  • International stone disease trends may not reflect local changes.
  • Understanding Tunisia's specific urolithiasis evolution is crucial.

Purpose of the Study:

  • To describe the 12-year evolution of pediatric urolithiasis in Tunisia.
  • To analyze changes in stone composition and contributing factors.

Main Methods:

  • Retrospective review of 133 children's urolithiasis cases (1994-2006).
  • Stone analysis via stereomicroscopy and infrared spectroscopy.
  • Epidemiological data collection.

Main Results:

  • Declining male prevalence (M:F ratio from 1.7 to 1.5).
  • Increasing urinary tract infections (UTIs) from 21.9% to 50%.
  • Rise in struvite (15.6% to 37.5%) and ammonium urate (12.5% to 25%) stones, linked to UTIs. Calcium oxalate monohydrate frequency decreased.

Conclusions:

  • Increased infectious risk factors correlate with rising struvite and ammonium urate stones.
  • Local epidemiological data is vital for understanding stone disease patterns.
Abstract

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