Related Experiment Video
Updated: Jul 3, 2026

A Minimally Invasive Model of Aortic Stenosis in Swine
Published on: October 20, 2023
Aortic stenosis in the Dogue de Bordeaux
M Höllmer1, J L Willesen, A T Jensen
1Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Dyrlaegevej 16, 1870 Frederiksberg C, Denmark.
Objectives:
To evaluate the occurrence of aortic stenosis and establish echocardiographic reference values in the Dogue de Bordeaux in Denmark.
Methods:
Fifty-three dogs were auscultated for evidence of a cardiac murmur and a full echocardiographic examination was performed. The criterion for the diagnosis of aortic stenosis was a peak aortic velocity greater than 2.5 m/s from a subcostal transducer location.
Results:
A left-basilar ejection murmur was detected in 38 (72 per cent) of the dogs. An aortic ejection velocity greater than 2.5 m/s was identified in 9 (17 per cent) of the dogs from a subcostal view. The aortic annulus in Dogue de Bordeaux was smaller than that considered normal in other breeds with comparable body size. Furthermore, a decreased aortoseptal angle was noticed in dogs with aortic stenosis.
Clinical Significance:
The Dogue de Bordeaux may be highly predisposed to aortic stenosis. The small aortic annulus noted in healthy and affected Dogue de Bordeaux and a decreased aortoseptal angle noted in affected dogs in this study might reflect key aetiological features in the development of aortic stenosis.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation I: Introduction
The Aorta
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
Mitral Stenosis I: Introduction
Aneurysm I: Introduction
Thoracic Aorta

