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Updated: Jul 3, 2026

Quantification of Monocyte Chemotactic Activity In Vivo and Characterization of Blood Monocyte Derived Macrophages
Published on: August 12, 2019
Monocyte chemoattractant protein-1 in acute coronary syndromes: complex vicious interaction
Basri Amasyali1, Sedat Kose, Hurkan Kursaklioglu
1Gulhane Military Medical School, Department of Cardiology, Etlik/Ankara, Turkey. dramasyali@yahoo.com
Abstract:
Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role both in the initiation and progression of atherosclerosis. MCP-1 is a unique cytokine produced by macrophages, smooth muscle cells and endothelial cells within atherosclerotic plaques and seems to be a reliable indicator of atherosclerotic plaque burden. Higher levels of MCP-1 have been associated with a poor prognosis and increased risk for death independent of other risk factors in patients with acute coronary syndromes. In this paper, we discussed the role of MCP-1 in the pathogenesis of acute coronary syndromes.
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