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Mesenchymal progenitor cell research: limitations and recommendations

Ross Summer1, Alan Fine

  • 1The Pulmonary Center, R-304, 715 Albany Street, Boston University School of Medicine, Boston, MA 02118-2394, USA.

Proceedings of the American Thoracic Society
|August 8, 2008
PubMed

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...