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Updated: Jul 3, 2026
11:02
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Special commentary: a call for intensive metabolic support.
Jeffrey I Mechanick1, Rene Chiolero
1Division of Endocrinology, Diabetes and Bone Disease, Mount Sinai School of Medicine, New York, New York, USA. jmechanick@aol.com
Current Opinion in Clinical Nutrition and Metabolic Care
|August 8, 2008
Summary
Optimizing critical care nutrition and metabolic support is crucial. This includes intensive insulin therapy, early nutrition (enteral and parenteral), and close monitoring for better patient outcomes.
Area of Science:
- Critical care medicine
- Clinical nutrition
- Metabolic support
Background:
- Clinical reviews highlight varied approaches to nutrition and metabolic support in critical care.
- Differences in practice exist between North America and Europe, potentially influenced by nutrient availability.
Purpose of the Study:
- To review current clinical practices in nutrition and metabolic support for critical care patients.
- To address recent advancements and divergent approaches in critical care nutrition.
Main Methods:
- This commentary synthesizes recent clinical reviews and expert opinions.
- It analyzes current trends in metabolic and nutritional interventions in intensive care units.
Main Results:
- Intensive insulin therapy significantly impacts metabolic support strategies.
- Combined enteral and parenteral nutrition approaches vary geographically.
- Specific patient populations (brain/heart failure) may benefit from tailored metabolic interventions.
- Intradialytic parenteral nutrition is a consideration for hemodialysis patients.
Conclusions:
- Routine implementation of intensive metabolic support in intensive care units is proposed.
- Key components include intensive insulin therapy, nutrition risk assessment, early nutritional provision (enteral/parenteral), and monitoring.
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