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Related Experiment Video

Updated: Jul 3, 2026

Recapitulating Suckling-to-Weaning Transition In Vitro using Fetal Intestinal Organoids

Recapitulating Suckling-to-Weaning Transition In Vitro using Fetal Intestinal Organoids

Published on: November 15, 2019

Which role for prebiotics at weaning?

Silvia Fanaro¹, Vittorio Vigi

¹Neonatal Intensive Care Unit, Section of Pediatrics, University of Ferrara, Ferrara, Italy. fnrslv@unife.it

Journal of Clinical Gastroenterology

|August 8, 2008

Summary

This summary is machine-generated.

Prebiotics can positively impact the gut microbiome during weaning, supporting infant health. Further research is needed to confirm these beneficial effects in large randomized trials.

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Area of Science:

Microbiology
Immunology
Gastroenterology

Background:

The intestinal microflora is crucial for human health, influencing digestion, immunity, and pathogen defense.
Weaning is a critical period for both gut flora development and immune system maturation.

Purpose of the Study:

To explore the role of prebiotics in modulating the gut microbiome during the delicate weaning phase.
To assess the effectiveness of prebiotics in promoting beneficial bacteria like bifidobacteria.

Main Methods:

Review of studies investigating prebiotic administration during weaning.
Analysis of microbiologic and clinical outcomes related to prebiotic use.

Main Results:

Prebiotics show promise in beneficially influencing the intestinal microflora at weaning.
Some studies report interesting microbiologic and clinical results regarding prebiotic effectiveness.

Conclusions:

Prebiotics offer a potential strategy to support gut health and immune development during weaning.
Larger randomized trials are necessary to validate the observed benefits of prebiotics.