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Related Concept Videos

Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Related Experiment Video

Updated: Jul 3, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Predicting strangulated small bowel obstruction: an old problem revisited.

Tim Jancelewicz1, Lan T Vu, Alexandra E Shawo

  • 1Department of General Surgery, University of California, San Francisco, 513 Parnassus Av. S320, San Francisco, CA 94143, USA.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
|August 8, 2008
PubMed
Summary
This summary is machine-generated.

Diagnosing strangulated small bowel obstruction (SBO) is challenging. Reduced CT wall enhancement, elevated white blood cell count, and peritoneal signs are key predictors of this critical condition.

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Murine Ileocolic Bowel Resection with Primary Anastomosis
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Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

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Last Updated: Jul 3, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

  • Medical imaging
  • Surgical diagnostics
  • Gastroenterology

Background:

  • Diagnosing intestinal strangulation in small bowel obstruction (SBO) is difficult.
  • No reliable clinical indicators currently exist to predict this condition.
  • This study aimed to identify predictive clinical indicators for strangulated intestine in SBO patients.

Purpose of the Study:

  • To determine which preoperative clinical indicators can independently predict strangulated intestine in patients with SBO.

Main Methods:

  • Reviewed medical records of 192 adult patients operated on for acute SBO (1996-2006).
  • Examined 72 preoperative clinical, laboratory, and radiologic findings.
  • Used multivariate logistic regression analysis to generate likelihood ratios for significant parameters.

Main Results:

  • Reduced CT wall enhancement was the strongest predictor of strangulation (LR 9.3, 56% sensitivity, 94% specificity).
  • Elevated white blood cell (WBC) count (LR 1.7) and guarding (LR 2.8) were moderately predictive.
  • 44 patients had strangulation requiring resection; 148 did not.

Conclusions:

  • Reduced CT wall enhancement, peritoneal signs, and elevated WBC count are independently predictive of bowel strangulation in SBO.
  • These findings aid in diagnosing this life-threatening condition.
  • Highlights the utility of CT imaging in SBO strangulation diagnosis.