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A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
Published on: November 7, 2017
[Neurological complications in uremia].
1Department of Neurology, Buddhist Dalin Tzu Chi General Hospital, Chia Yi, Taiwan. csfong@seed.net.tw
Acta Neurologica Taiwanica
|August 9, 2008
Summary
Neurological complications in uremia, including encephalopathy and neuropathy, persist despite hemodialysis. Kidney transplantation and its treatments can also trigger neurological issues, impacting patient mortality.
Area of Science:
- Nephrology
- Neurology
Context:
- Uremia presents significant neurological challenges, contributing to mortality.
- Neurological complications like uremic encephalopathy and neuropathy often inadequately respond to hemodialysis.
Purpose:
- To review the clinical, pathophysiological, and therapeutic aspects of neurological complications in uremia.
- To explore central and peripheral nervous system disorders and myopathy associated with uremia.
Summary:
- Hemodialysis can induce various neurological complications, including Wernicke's encephalopathy, dysequilibrium syndrome, and cerebrovascular accidents.
- Kidney transplantation and immunosuppressive therapy may lead to rejection encephalopathy and reversible posterior leukoencephalopathy.
Impact:
- Understanding these complications is crucial for improving patient outcomes in uremia.
- This review highlights the complex relationship between renal failure, treatment modalities, and neurological health.
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