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Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

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Related Experiment Video

Updated: Jul 3, 2026

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

Acinetobacter-- serious danger for burn patients.

J Babík1, L Bodnárová, K Sopko

  • 1Clinic for Burns and Reconstructive Surgery, Kosice-Saca, Slovakia. jbabik@nemocnicasaca.sk

Acta Chirurgiae Plasticae
|August 9, 2008
PubMed
Summary

Acinetobacter baumannii infections increased in burn patients, showing rising multi-drug resistance. Surveillance identified an outbreak and risk factors, prompting further investigation into this critical pathogen.

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Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
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Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

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Last Updated: Jul 3, 2026

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Burn Surgery

Background:

  • Acinetobacter baumannii (Ab) is a multi-drug-resistant pathogen increasingly isolated from burn patients.
  • Sporadic isolation of Ab in Intensive Care Units (ICU) since 1992 showed a rapid increase in resistant strains by 1999.
  • Colonization rates of Ab in hospitalized and ICU patients rose significantly between 2003 and 2004.

Purpose of the Study:

  • To investigate the epidemiology of an Acinetobacter baumannii outbreak in burn patients.
  • To identify risk factors associated with colonization and infection by multi-drug-resistant Ab strains.
  • To establish intensive surveillance for Ab isolates following an observed increase in resistance.

Main Methods:

  • Retrospective study of burn patients admitted to a specialized clinic between 2003 and 2006.
  • Analysis of bacterial isolate trends, antimicrobial resistance patterns, and patient infection types.
  • Epidemiological investigation and risk factor assessment for Ab colonization and infection.

Main Results:

  • A significant increase in Acinetobacter (Acb) strains, identified as multi-drug-resistant, was confirmed.
  • Antimicrobial resistance to Ampicilin/Sulbactam, Gentamycin, and Meropenem rose sharply after 2003.
  • In 2006, multi-drug-resistant Ab was recorded in 11% of patients, with 2 deaths due to sepsis.

Conclusions:

  • Acinetobacter baumannii poses a significant threat to burn patients due to increasing multi-drug resistance.
  • The study highlights the need for robust surveillance and infection control measures for Ab in healthcare settings.
  • Understanding the epidemiology and risk factors is crucial for managing Ab outbreaks in vulnerable patient populations.