Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patch testing with amalgam at various concentrations.

J von Mayenburg1, J Rakoski, C Szliska

  • 1Department of Dermatology, Technical University of Munich, FRG.

Contact Dermatitis
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food-induced anaphylaxis and cofactors - data from the anaphylaxis registry.

Allergologie select·2018
Same author

[Should metal alloy discs be used for patch testing in suspected metal implant intolerance reaction?].

Der Orthopade·2015
Same author

[Facial allergic contact dermatitis. Data from the IVDK and review of literature].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2008
Same author

IgE-mediated type-I-allergy against red wine and grapes.

Allergy·2007
Same author

[Pseudoxanthoma elasticum].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2006
Same author

In vitro basophil activation using CD63 expression in patients with bee and wasp venom allergy.

Journal of investigational allergology & clinical immunology·2006

This study investigated mercury and amalgam allergies in 27 patients. Ten out of thirteen women with amalgam allergies reacted to a 5% concentration, suggesting this as a key testing level.

Area of Science:

  • Dermatology
  • Allergology
  • Toxicology

Background:

  • Mercury and its compounds, including dental amalgam, are known contact allergens.
  • Previous patch testing identified patients with positive reactions to mercury screening allergens.
  • The optimal concentration for patch testing amalgam allergies requires further definition.

Purpose of the Study:

  • To evaluate patient reactions to various mercury patch test preparations.
  • To determine the lowest effective concentration of amalgam for patch testing.
  • To explore the clinical significance and demographic patterns of amalgam reactivity.

Main Methods:

  • Twenty-seven patients with positive D3 reactions to mercury screening allergens underwent patch testing.
  • Testing included 13 mercury preparations (6 inorganic, 7 organic) and 20% amalgam in petrolatum.

Related Experiment Videos

  • Patients reacting to amalgam were further tested with serially reduced concentrations.

    • Main Results:

    • Thirteen patients (all female) reacted positively to 20% amalgam.
    • Of these, 10 patients reacted to 5% amalgam concentration.
    • Reactions were observed down to 1% concentration in two patients.

    Conclusions:

    • A 5% amalgam concentration appears significant for patch testing in sensitive individuals.
    • The study highlights a female predominance in amalgam reactivity.
    • Further research is recommended on the clinical relevance and gender distribution of amalgam allergy.