Related Experiment Video
Updated: Jul 3, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Fast intersections on nested tetrahedrons (FINT): An algorithm for adaptive finite element based distributed
Jae Hoon Lee1, Amit Joshi, Eva M Sevick-Muraca
1Department of Radiology, Baylor College of Medicine, Photon Migration Laboratory, One Baylor Plaza, BCM 360, Houston, TX 77030, USA.
Abstract:
A variety of biomedical imaging techniques such as optical and fluorescence tomography, electrical impedance tomography, and ultrasound imaging can be cast as inverse problems, wherein image reconstruction involves the estimation of spatially distributed parameter(s) of the PDE system describing the physics of the imaging process. Finite element discretization of imaged domain with tetrahedral elements is a popular way of solving the forward and inverse imaging problems on complicated geometries. A dual-adaptive mesh-based approach wherein, one mesh is used for solving the forward imaging problem and the other mesh used for iteratively estimating the unknown distributed parameter, can result in high resolution image reconstruction at minimum computation effort, if both the meshes are allowed to adapt independently. Till date, no efficient method has been reported to identify and resolve intersection between tetrahedrons in independently refined or coarsened dual meshes. Herein, we report a fast and robust algorithm to identify and resolve intersection of tetrahedrons within nested dual meshes generated by 8-similar subtetrahedron subdivision scheme. The algorithm exploits finite element weight functions and gives rise to a set of weight functions on each vertex of disjoint tetrahedron pieces that completely cover up the intersection region of two tetrahedrons. The procedure enables fully adaptive tetrahedral finite elements by supporting independent refinement and coarsening of each individual mesh while preserving fast identification and resolution of intersection. The computational efficiency of the algorithm is demonstrated by diffuse photon density wave solutions obtained from a single- and a dual-mesh, and by reconstructing a fluorescent inclusion in simulated phantom from boundary frequency domain fluorescence measurements.
Related Concept Videos
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Finding Volume Using Cross-Sectional Area
Fast Decoupled and DC Powerflow
Distributed Loads: Problem Solving
Mesh Analysis
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
