Characteristics of the bladder in infants with urinary tract infections: an ultrasound study

Ji-Xian Liu1, Vivian Yee-Fong Leung, Winnie Chiu-Wing Chu

  • 1Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.

Pediatric Radiology
|August 9, 2008
PubMed

Insights

Urinary tract infections (UTI) in infants are linked to impaired bladder function, showing smaller maximal bladder volumes and increased residual volumes. Ultrasound measurements can objectively assess bladder changes during UTI in infants.

Area of Science:

  • Pediatric Urology
  • Diagnostic Imaging
  • Infectious Diseases

Background:

  • Urinary tract infections (UTI) are known to cause impaired bladder function in patients.
  • Urodynamic (UD) studies demonstrate this impairment, but are rarely performed in infants.
  • Infants with UTI often present with subtle signs, making early diagnosis challenging.

Purpose of the Study:

  • To evaluate bladder function in infants diagnosed with UTI.
  • To utilize a dynamic ultrasound (US) protocol to measure key bladder parameters.
  • To compare these parameters against those of healthy, age-matched infants.

Main Methods:

  • Recruited 57 infants with proven UTI and 63 healthy controls.
  • Measured maximal bladder volume (MaxBV) before voiding.
  • Measured residual volume (RV) and bladder wall thickness (BWT) after voiding using ultrasound.

Main Results:

  • Infants with UTI exhibited smaller MaxBV (34.89 ml) compared to controls (42.91 ml).
  • UTI infants had significantly larger RV (3.46 ml vs. 1.51 ml) and BWT (4.21 mm vs. 3.68 mm).
  • These differences were statistically significant (P<0.05).

Conclusions:

  • Smaller bladder volumes, larger residual volumes, and thicker bladder walls in infants with UTI suggest bladder instability and edema.
  • Ultrasound measurement of bladder parameters offers an objective method for clinical diagnosis.
  • US assessment can aid in objectively evaluating bladder function during post-treatment follow-up.
Abstract

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