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06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Takotsubo cardiomyopathy in acute ischemic stroke
Sohei Yoshimura1, Kazunori Toyoda, Tomoyuki Ohara
1Department of Medicine, Cerebrovascular Division, National Cardiovascular Center, Suita, Osaka, Japan.
Annals of Neurology
|August 9, 2008
Summary
Takotsubo cardiomyopathy is a frequent complication in acute ischemic stroke patients, particularly in older women with insular cortex damage. This condition often develops soon after stroke onset and is typically asymptomatic.
Area of Science:
- Cardiology
- Neurology
- Internal Medicine
Background:
- Takotsubo cardiomyopathy, a transient left ventricular dysfunction, is a recognized complication of subarachnoid hemorrhage.
- Acute ischemic stroke is a critical neurological event with various potential complications.
Purpose of the Study:
- To identify the clinical characteristics of patients experiencing takotsubo cardiomyopathy following an acute ischemic stroke.
- To understand the prevalence and presentation of takotsubo cardiomyopathy in stroke patients.
Main Methods:
- A case series of seven patients diagnosed with takotsubo cardiomyopathy post-acute ischemic stroke.
- Electrocardiographic and echocardiographic findings were used for diagnosis.
- Review of nine previously published cases of takotsubo cardiomyopathy in stroke patients.
Main Results:
- All seven patients were elderly women, with stroke infarcts often involving the insular cortex or vertebrobasilar territory.
- Cardiomyopathy symptoms appeared within 10 hours of stroke onset in most cases, and it was frequently asymptomatic.
- Elevated plasma brain natriuretic peptide levels were observed in all patients.
Conclusions:
- Takotsubo cardiomyopathy is a notable complication of acute ischemic stroke, often occurring early and asymptomatically.
- Female sex and insular cortex damage are predominant features in stroke patients who develop takotsubo cardiomyopathy.
- This highlights the importance of cardiac monitoring in stroke patients, especially in specific demographic and lesion location groups.
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