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Typhoid ileal perforation: analysis of morbidity and mortality in 89 children

S O Ekenze1, P E Okoro, C C Amah

  • 1Department of Pediatric Surgery, University of Nigeria Teaching Hospital, Enugu. soekenze@yahoo.com

Nigerian Journal of Clinical Practice
|August 12, 2008
PubMed

Insights

Typhoid ileal perforation in children leads to high morbidity and mortality, especially in developing nations. Early surgical intervention and presentation are crucial for improving outcomes in pediatric cases.

Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Gastroenterology

Background:

  • Typhoid ileal perforation remains a significant health issue in developing countries.
  • Despite advancements, pediatric outcomes for this condition are often poor.

Purpose of the Study:

  • To assess the morbidity and mortality associated with childhood typhoid ileal perforation.
  • To evaluate outcomes at a tertiary referral center in southeast Nigeria.

Main Methods:

  • A retrospective analysis of 89 children who underwent surgery for typhoid ileal perforation.
  • Data collected over a 10-year period (1995-2004) at the University of Nigeria Teaching Hospital, Enugu.

Main Results:

  • The study included 89 children (60.7% boys), with a mean age of 9.1 years.
  • Common symptoms included prolonged fever and abdominal pain; vomiting was frequent in younger children (<5 years).
  • Postoperative complications included surgical site infections (46.1%), chest infections (23.6%), and reperforation (21.3%), leading to an overall mortality of 19.1%.

Conclusions:

  • Childhood typhoid ileal perforation is linked to substantial morbidity and mortality.
  • Early presentation and prompt surgical intervention are key to improving patient outcomes.
Abstract

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