Related Experiment Video
Updated: Jul 2, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
How fast is too fast? a practice change in umbilical arterial catheter blood sampling using the Iowa Model for
Myrna Gordon1, Lisa Bartruff, Sara Gordon
1University of Iowa Children's Hospital, University of Iowa Hospitals and Clinics, Iowa, USA. myrna-gordon@uiowa.edu
Insights
Implementing evidence-based practice for umbilical artery catheters in premature infants can improve care. Changing catheter practices may reduce risks like intraventricular hemorrhage and periventricular leukomalacia.
Area of Science:
- Neonatal Medicine
- Pediatric Critical Care
- Evidence-Based Practice
Background:
- Umbilical artery catheters (UACs) are crucial for monitoring very low birth-weight infants.
- Rapid blood withdrawal or flushing of UACs can negatively impact cerebral blood flow.
- Altered cerebral blood flow is linked to serious neonatal complications like intraventricular hemorrhage and periventricular leukomalacia.
Purpose of the Study:
- To modify clinical practice regarding UAC blood withdrawal and flushing rates.
- To enhance patient safety and outcomes for very low birth-weight infants.
Main Methods:
- Utilized the Iowa Model of Evidence-Based Practice to Promote Quality Care.
- Integrated current research on UAC effects on cerebral blood flow.
- Incorporated expert opinion, scientific principles, and theories.
- Developed and implemented a new standard of practice.
- Provided staff education on the revised protocol.
Main Results:
- A new standard of practice for UAC management was established.
- Clinical staff were educated on the updated procedures.
- The study aimed to reduce potential adverse events associated with UAC manipulation.
Conclusions:
- Evidence-based practice is a viable framework for improving neonatal care protocols.
- Modifying UAC practices can mitigate risks of cerebral blood flow alterations.
- This initiative sought to decrease morbidity and mortality in vulnerable premature infants.
Abstract:
A multidisciplinary team at the University of Iowa Children's Hospital utilized the Iowa Model of Evidence-Based Practice to Promote Quality Care as a basis for changing practice related to the rate of drawing and flushing umbilical artery catheters in very low birth-weight infants. Research indicates that rapid withdrawal of blood or flushing of catheters that are placed in the aorta can affect cerebral blood flow velocity, volume, and oxygenation. Alteration of cerebral blood flow in premature infants has been correlated with the incidence of intraventricular hemorrhage and periventricular leukomalacia, which can be a significant cause of morbidity and mortality in this population. Using this research as a guide, along with expert opinion, scientific principles, and theories, a new standard of practice was written, and the staff educated.
Related Concept Videos
Pre-Procedural Guidelines for Assessing Blood Pressure
Cardiac Catheterization IV: Nursing Management
Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:

