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Dermatofibrosarcoma protuberans of the vulva
J F Leake1, J Buscema, K R Cho
1Department of Gynecology and Obstetrics, Johns Hopkins Hospital, Baltimore, Maryland 21205.
Gynecologic Oncology
|June 1, 1991
Summary
Dermatofibrosarcoma protuberans of the vulva is a rare skin cancer. Complete surgical removal is key to preventing recurrence, with frozen section margins aiding in achieving this goal.
Area of Science:
- Dermatologic oncology
- Surgical pathology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade cutaneous sarcoma originating in the dermis.
- DFSP of the vulva is particularly uncommon, posing diagnostic and therapeutic challenges.
Observation:
- This report details two new cases of vulvar dermatofibrosarcoma protuberans.
- One patient presented with a rare fibrosarcomatous component within the DFSP.
Findings:
- Wide local excision is the standard treatment for DFSP.
- Microscopic tumor infiltration at the margins contributes to high local recurrence rates.
- Frozen section analysis of surgical margins can improve complete resection rates.
Implications:
- Accurate margin assessment, potentially via frozen sections, is crucial for optimizing surgical outcomes in vulvar DFSP.
- The occurrence of fibrosarcoma within DFSP highlights the potential for histologic variability and underscores the need for thorough pathological examination.