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Milk allergy and bottles over the back fence: two single patient trials
Bruce Arroll1, Harry Pert, Gordon Guyatt
1Department of General Practice and Primary Health Care, Faculty of Medical & Health Sciences, University of Auckland, New Zealand. b.arroll@auckland.ac.nz.
Objective:
To determine if allergy to cows milk was responsible for symptoms in two children.
Design:
Single patient trial.
Setting:
General Practice in New Zealand.
Participants:
Two children aged about 6 months
Intervention:
Alternating bottles of soya-based milk and cow's milk provided by neighbours over their back fence.
Main Outcome Measures:
Presence of diarrhea, irritability, rash and wheeze.
Results:
After 4 cycles of soya-based milk and cows milk one child proved to have a milk allergy and one did not.
Conclusion:
A systematic approach enabled conclusive diagnoses in both children.
