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The effects of increasing obesity on outcomes of vascular surgery
Nader Khandanpour1, Matthew P Armon, Rob Foxall
1Vascular Surgery Department, Norfolk and Norwich Vascular Unit, Norfolk and Norwich University Hospital, Norwich, UK. nkh950@yahoo.com
Insights
Vascular surgery patients are increasingly obese. Morbidly obese patients experience longer operation times and higher infection rates, particularly for abdominal aortic aneurysm repair, though overall outcomes remain similar in this study.
Area of Science:
- Vascular Surgery
- Obesity Research
- Surgical Outcomes
Background:
- Increasing prevalence of obesity in the general population.
- Potential impact of rising obesity rates on vascular surgery patient demographics and outcomes.
Purpose of the Study:
- To investigate the trend of increasing obesity among vascular surgery patients.
- To determine if morbid obesity (BMI > 35 kg/m2) affects surgical outcomes, including operation duration, length of stay, complications, and mortality.
Main Methods:
- Retrospective analysis of 1,105 vascular procedures (infrainguinal bypass, carotid endarterectomy, AAA repair) from 1996-2006.
- Patients stratified by Body Mass Index (BMI): underweight (<18.5), morbidly obese (>35), and control (18.5-35).
- Outcomes adjusted for confounding variables (admission mode, diabetes, cardiac history, renal function, smoking).
Main Results:
- Incidence of morbid obesity in vascular patients increased linearly from 1.3% to 9% over 10 years.
- Morbidly obese patients had significantly longer operation durations for AAA repair (189.8 vs. 158.4 min, p < 0.014).
- Higher infection rates observed in morbidly obese patients, significantly so for AAA repair (43.5% vs. 34.8%, p < 0.004).
Conclusions:
- Vascular surgery patient population is experiencing a progressive increase in obesity.
- Morbid obesity is associated with increased operative time and infectious complications, particularly in AAA repair.
- Despite these challenges, morbid obesity did not significantly worsen overall surgical outcomes or mortality in this cohort.
Abstract:
The aim of this study was to determine whether vascular patients are becoming progressively more obese and whether morbid obesity affects outcomes from vascular surgery. Data for the index vascular procedures of infrainguinal bypass, carotid endarterectomy, and abdominal aortic aneurysm (AAA) repair were collected in a computer database for 1996-2006. Body mass index (BMI) was stratified into <18.5 kg/m2 as underweight, >35 kg/m2 as morbidly obese, and other as control (18.5 < BMI < 35). The data were analyzed with respect to operation duration, length of stay, complication rates, and mortality rates. Results were adjusted for potential confounding variables, including mode of admission, diabetes, cardiac history, renal function, and smoking. A total of 1,317 patients were reviewed, and 1,105 cases were deemed suitable for analysis. The incidence of morbid obesity increased in a linear manner from 1.3% to 9% over the 10-year period. The operation duration was longer for morbidly obese subjects compared with normals. This was only statistically significant for AAA repair category, with a mean operating time of 158.4 +/- 65.5 min for patients with BMI <35 kg/m2 vs. 189.8 +/- 92.2 min for morbidly obese patients (p < 0.014). Infection rates were consistently higher in the morbidly obese group; however, this reached a statistically significant rate among AAA repair cases (43.5% [n = 16] vs. 34.8% [n = 159], p < 0.004). There were no significant differences in other complications, graft failure, length of stay, or mortality. Vascular patients are becoming progressively more obese. Procedures performed on morbidly obese subjects take longer, and these patients have higher rates of infectious complications. This is mainly attributable to AAA. This did not translate into poorer final outcomes in this study, although significant differences might emerge from a larger sample.
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