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Cerebral Hemispheres

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The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

Cerebrum: Anatomical Overview II

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The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...

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Anatomy of the Brain: Major Regions

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Commissural malformations: beyond the corpus callosum.

T Smith¹, A Tekes, E Boltshauser

¹Division of Pediatric Radiology, Russell H. Morgan-department of Radiology and Radiological Science, Johns Hopkins Hospital, 600, North Wolfe Street, Nelson Basement B-173, Baltimore, MD 21287-0842 , USA.

Journal of Neuroradiology = Journal De Neuroradiologie

|August 12, 2008

Summary

Corpus callosum agenesis often indicates other midline commissural anomalies. Advanced imaging like MRI and DTI is crucial for comprehensive diagnosis, even in preterm infants.

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Area of Science:

Neuroscience
Radiology
Medical Imaging

Background:

Corpus callosum agenesis is a common finding in congenital midline anomalies.
It is often associated with other malformations of the brain's commissural pathways.

Observation:

Midline commissural anomalies extend beyond the corpus callosum.
Anterior and hippocampal commissures may also be affected by agenesis or hypogenesis.

Findings:

Magnetic resonance imaging (MRI) is the most sensitive method for detecting commissural anomalies.
Diffusion tensor imaging (DTI) aids in identifying subtle or absent commissures, including in neonates.

Implications:

Comprehensive evaluation of all midline commissures is essential for accurate diagnosis.
Early and precise identification of these anomalies impacts patient management and prognosis.
Advanced imaging techniques improve diagnostic capabilities in neonatal neurology.