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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

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Related Experiment Video

Updated: Jul 2, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Midterm outcome predictors for lower extremity atherectomy procedures.

Timur P Sarac1, Ozcan Altinel, Mohsen Bannazadeh

  • 1Department of Vascular Surgery, The Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA.

Journal of Vascular Surgery
|August 12, 2008
PubMed
Summary

SilverHawk atherectomy for lower extremity procedures improves symptoms but shows decreased durability. Diabetes, renal disease, tobacco use, and tissue loss are linked to poorer outcomes and patency loss.

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Last Updated: Jul 2, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Medical Devices

Background:

  • Atherectomy devices have shown variable performance in treating lower extremity peripheral artery disease.
  • The SilverHawk atherectomy device is utilized for endovascular intervention in lower limb arteries.

Purpose of the Study:

  • To evaluate the midterm success of the SilverHawk atherectomy device in lower extremity procedures.
  • To identify predictors of success and adverse outcomes associated with SilverHawk atherectomy.

Main Methods:

  • Retrospective review of 73 patients undergoing lower extremity atherectomy with the SilverHawk device between 2004 and 2006.
  • Analysis of patient demographics, vessel characteristics, and postoperative outcomes.
  • Kaplan-Meier and Cox Proportional Hazards modeling to determine patency, limb salvage, and survival rates and associated factors.

Main Results:

  • 167 vessels in 73 patients were treated, with 78% presenting with intermittent claudication and 71% with rest pain.
  • One-year cumulative rates: primary patency 43%, assisted primary patency 49%, secondary patency 57%, limb salvage 75%, and survival 90%.
  • Multivariable analysis identified tobacco use, renal disease, diabetes, and tissue loss as predictors of patency loss, with diabetes and tissue loss also associated with limb loss.

Conclusions:

  • SilverHawk atherectomy is a safe and effective treatment for improving lower extremity symptoms.
  • Midterm durability is limited, with significant patency and limb loss observed over time.
  • Diabetes, renal disease, tobacco use, and tissue loss are associated with inferior outcomes, necessitating careful patient selection and management.