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Related Experiment Videos

Colon perforation due to cholesterol embolism.

W R Anderson1, T Braverman

  • 1Department of Pathology, Hennepin County Medical Center, Minneapolis, MN 55415.

Human Pathology
|August 1, 1991
PubMed
Summary

Cholesterol embolization syndrome can affect the gastrointestinal tract, but rarely causes severe outcomes. This case details a fatal colon perforation and peritonitis resulting from intestinal cholesterol emboli.

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Area of Science:

  • Cardiovascular Medicine
  • Gastroenterology
  • Pathology

Background:

  • Systemic atheroembolism involves cholesterol crystal emboli lodging in small arteries.
  • Gastrointestinal (GI) tract involvement is a recognized, though infrequent, complication of atheroembolism.

Observation:

  • A 65-year-old patient presented with symptoms suggestive of atheroembolism.
  • The patient subsequently developed signs of bowel perforation.

Findings:

  • The patient experienced cholesterol embolization to the intestinal tract.
  • This led to a critical complication: perforation of the colon.
  • The perforation resulted in fatal peritonitis, highlighting a rare catastrophic outcome.

Implications:

  • This case underscores the potential for severe GI complications from atheroembolism.
  • It emphasizes the importance of considering intestinal ischemia and perforation in patients with atheroembolism.
  • Highlights a rare but fatal presentation of cholesterol embolization syndrome affecting the GI tract.

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